Featured at AACR Annual Meeting: VisionGate Lung Cancer 3D Imaging Research

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Photo by Anne Weston supergme.wordpress.com

Health Editor’s Note: The earliest discovery of cancer cells is key to treatment and cure of cancers.  VisionGate Lung Cancer 3D cellular Imaging Research seeks to detect changes in surrounding “non-cancerous” cells that cancer cells cause by their very existence. Most methods of discovery of cancer cells focus on finding the actual cancer cell, but this imaging research project looks for changes nearby cancer cells can cause. A different approach to cancer detection and hopefully another avenue for earliest detection….Carol 

VisionGate Lung Cancer 3D Cellular Imaging Research to be Featured as a Late-Breaking Abstract at the AACR Annual Meeting 2018

SEATTLE, WA (April 12, 2018) – VisionGate, Inc., a clinical stage oncology pharmaceutical and diagnostics company, is pleased to announce that new lung cancer 3D cellular imaging research findings will be presented at the upcoming 2018 American Association of Cancer Research (AACR) annual meeting in Chicago, Illinois from April 14-18, 2018.

The abstract presentation includes a breakthrough research study using the Company’s Cell-CT™ platform 3D cellular imaging technology to detect subtle alterations in cellular and nuclear architecture in non-cancerous cells caused by the “field effect” that cancer cells exert on their microenvironment – known as Malignancy Associated Change (MAC).

“We are excited to present this important study at this year’s AACR Annual Meeting,” said Michael Meyer, VisionGate’s Chief Technology Officer, “The acceptance of this abstract and its results represent significant progress that VisionGate continues to make in the pursuit of innovation in the early detection and treatment of cancer.”

VisionGate, Inc. is pleased to be attending the AACR Annual Meeting in Chicago April 14-18 where the Company will be presenting late-breaking research:

Title: The Malignancy Associated Change Hypothesis Tested Through 3D Cellular Imaging

Presentation Number: Abstract #LB-175

Session: Late-Breaking Research: Epidemiology and Prevention

Date and Time: Monday, April 16, 2018, 1:00 p.m. – 5:00 p.m. CDT, Chicago

Location: Poster Section 44, Poster Board 18

About VisionGate, Inc.

VisionGate is a clinical stage oncology pharmaceutical and diagnostics company focused on the early detection and prevention of cancer. Our lead investigative pharmaceutical drug is oral iloprost, currently in clinical development for the treatment of pre-cancerous bronchial dysplasia and the prevention of lung cancer following a successful Phase 2 clinical trial. The LuCED® lung test will be the companion diagnostic for oral iloprost. VisionGate’s proprietary LuCED lung test is a non-invasive liquid biopsy diagnostic test in development for detection of early-stage lung cancer, demonstrating exquisite sensitivity and specificity in blinded clinical studies. This non-invasive sputum test is performed on the world’s first automated 3D single cell imaging and analysis technology, the Cell-CT™ platform, named aptly because it is similar in principle to taking a computed tomography (CT) scan of individual cells, but using visible light without harmful radiation. With 176 issued patents in 13 countries, VisionGate expects to play a leading role in the battle against lung cancer – the world’s number one cancer killer. VisionGate, Inc. is led by Dr. Alan Nelson, physicist, bioengineer, and serial entrepreneur who previously developed the world’s first and only automated screening test to detect cervical cancer, marketed globally today as FocalPoint by Becton Dickinson. The LuCED lung test is a product in development and is not currently available commercially.


About the Cell-CT™ 3D Imaging Platform

The automated Cell-CT™ 3-Dimensional Single Cell Imaging and Analysis Platform is the enabling technology which produces high-resolution 3D images of individual cells using a technique called optical computed tomography. This 3D optical CT platform breaks new ground in the field of quantitative cell analysis by its unique ability to computationally reconstruct the true 3D internal structure of cells based on molecular optical absorption densities. The Cell-CT platform produces high-resolution 3D images of individual cells and measures hundreds of critical disease indicators in each cell. Together with advanced artificial intelligence (AI) algorithms, these produce accurate cell classifications that aid in the early detection of disease. Additionally, the Cell-CT platform has the potential to deliver molecular and genetic biosignatures of disease longitudinally to complement drug development in the biopharma services arena. Cells are not placed on slides, but rather, they are suspended in fluid (liquid biopsy) and injected through a micro-capillary tube that permits multiple viewing perspectives around 360°. The Cell-CT platform is a device under development and not currently cleared in the US.

5 COMMENTS

  1. Adrian2MiL18, I know that mutations are affecting which antibiotics are effective and which ones have become ineffective. We see the end results of evolution….critters that adapt, live, then breed, then create more and better critters….sometimes a mutation, such as a longer tongue in a butterfly will help it to adapt to getting more nectar from deeper flowers that other butterflies cannot reach….this happens all the time in beings that have complicated structures, organ systems, etc. It is way more easy for a mutation to occur in a one celled bacteria and in a virus, that does not every have a nucleus for replication of itself, thus it invades our cells or the cells of animals and make us or the animals sick in order to make more of itself. I also know that humans are working on various viruses and bacteria to cause changes/mutations that do not occur naturally and these are happening (all of a sudden.) This could be used for negative reasons….Carol

  2. Continued…..we are definitely doing something wrong with the way we treat our environment, foods, water, air, etc. We are seeing lung cancer in women when lung cancer used to be found for the most part in men. We are seeing nonsmokers develop lung cancer…..that does not seem possible, does it? When a hospital has become infectious and gives a patient an infection, that is another fact that is hard to swallow. People are pushed out of hospitals, possibly long before they should be discharged, with the excuse that they might develop an infection while in the hospital. When I was a nursing student, rooms were clean, sanitary protocols were followed to the letter and no one went home sicker than when he or she came in…..We are facing challenges and have to develop ways to stay on top…..Carol

  3. Around 50 years ago, diagnose somebody with cancer was almost a weirdness or like find people sick by infections in hospitals. Some very strange has been happening with diseases from that time until today… Cancer, HIV and so on, it seems they come on the scene from nowhere…

    • Adrian2MiL18, As time goes by the field of medicine and other fields of industry find new ways to diagnosis and test for diseases and sometimes there are new, effective treatments. We have bacteria that are mutating into forms that are not being affected by the tried and true antibiotics. People are living longer and are dying from illnesses that they would have never lived long enough to get (Alzheimer’s is a prime one of these.) A diagnosis of cancer was almost always a death sentence and now people can have stage IV cancer and survive. Continued…..

    • Carol, the bacteria that are mutating into forms that are not being affected by the tried and true antibiotics arfe mutating by himself or somebody is helping them ??? … because we are using antibiotics since little more that a century…. the mutations in the nature taking much more than that…. at least it’s suspicious.
      Greetings

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