Vaping and Nicotine E-Cigarettes Worse For Heart Than Traditional Cigarettes

photo by Carol Duff

Health Editor’s Note:  VT has been following the EVALI illness associated with vaping.  Illness and many deaths have been the result of vaping.  It has been found that vaping and e-cigarettes cause more harm to the coronary (heart) microvacular (small blood vessels) than regular cigarettes.  People have stopped smoking tobacco in favor of vaping and the use of e-cigarettes with the idea that vaping/e-cigarettes are less harmful. While vaping may cause less risk of cancer with less tar in the lungs than traditional cigarettes, there are negative effects that occur in the cardiovascular (heart and blood vessels). Vaping and e-cigarettes are not healthy alternatives to just stopping the use of tobacco. Smoking and nicotine are health hazards, plain and simple….Carol   

Vaping Worse for Heart Than Cigarettes?

By Nicole Lou, Staff Writer/MedPage Today

E-cigarette smokers were worse off than conventional cigarette smokers in terms of coronary microvascular vascular function, researchers found in a small study.

Physiologic changes between rest and a hand-grip exercise to simulate stress showed regular tobacco cigarette and e-cigarette users had fairly similar myocardial blood volume responses to stress right after a smoking session compared with non-smoking controls (-4.3% and -0.9% vs +2.7% from baseline).

However, the e-cigarette group did worse than the combustible cigarette group in change in myocardial blood velocity (-4.7% vs +34.7% for tobacco, P=0.005) and myocardial blood flow (-5.8% vs +30.5%, P=0.023).

And both groups were worse on those two measures than the controls (+66.8% and +72.1%, respectively), according to Florian Rader, MD, MSc, of the Smidt Heart Institute at Cedars-Sinai Medical Center, Los Angeles, and colleagues.

The study results were released ahead of presentation later this week as an oral abstract at the American Heart Association meeting in Philadelphia.

“The blunting of stress-induced increase of coronary blood flow associated with chronic e-cig use in humans is consistent with what is being seen in other vascular systems, in animals, and after acute use: endothelial dysfunction at the level of (or exceeding) that of combustible cigarette use,” commented Matthew Springer, PhD, of the University of California, San Francisco, who was not involved in the research.

“We are seeing an emerging story that regardless of whether vaping involves less risk of cancer and less tar in the lungs than traditional smoking, the cardiovascular effects are substantial and indicate a level of cardiovascular risk that one really wants to avoid,” wrote Springer in an email to MedPage Today.

Vaping-related acute lung damage, dubbed “EVALI,” has already killed dozens, most of them young people under age 30. Recently, vitamin E acetate has been proposed as the common denominator among bronchoalveolar lavage samples of those who have fallen sick after e-cigarette or vape use.

Rader’s group noted that e-cigarettes and vaping devices rely on battery-powered aerosolization that delivers a mix of small molecules that can cross the alveolar-capillary barrier and enter into the circulation.

“What makes e-cigarettes so harmful to the heart and lungs is not just nicotine,” said Rader in a press release. “It’s the completely unknown bucket of manufactured products used to form vapors that is likely causing the most harm. This is what we believe is underlying the current public health problem.”

“It’s very clear that e-cigarettes have a detrimental effect on myocardial endothelial function, even a worse effect than classical cigarettes,” commented Daniel Duprez, MD, PhD, of the University of Minnesota, Minneapolis. And endothelial dysfunction, in turn, can lead to increased blood pressure and mark the beginning of atherosclerotic disease, he told MedPage Today.

“This is just adding to the evidence that in terms of heart disease, e-cigarettes are just as bad as cigarettes and might be even worse. That’s the picture emerging for lung disease, too,” said Stanton Glantz, PhD, also of the University of California, San Francisco, who was not involved in the study.

A total of 30 people participated in the present study, undergoing myocardial contrast echocardiography after overnight abstinence from smoking. Average age was 28 years, and this was a group of healthy adults who had normal tension and were not obese. There were only eight women in the study.

“However, the gender ratio in the vaping group was similar to that in the smoking group, so the observation that the vapers had essentially no myocardial flow response to stress, compared with a blunted but still present response in smokers, is especially strong and implies that switching from smoking to vaping may involve increased risks in some aspects of cardiovascular health,” Springer emphasized.

He pointed out that the authors didn’t report whether their non-cigarette-smoking participants were exposed frequently to secondhand smoke or are marijuana smokers.

Nevertheless, the public may have been getting the message that EVALI cases seem to mostly be associated with THC products and associated ingredients, potentially leading people who vape nicotine products to feel “immune” to all the risks of vaping — and that’s wrong, according to Springer.

There are other ways in which vaping nicotine e-cigarettes can lead to cardiovascular and pulmonary harm, he emphasized. “The public needs to hear about studies like this.”

The study was funded in part by the Tobacco Related Disease Research Program.

Springer, Glantz, and Duprez disclosed no relevant relationships with industry.

Primary Source

Carol graduated from Riverside White Cross School of Nursing in Columbus, Ohio and received her diploma as a registered nurse. She attended Bowling Green State University where she received a Bachelor of Arts Degree in History and Literature. She attended the University of Toledo, College of Nursing, and received a Master’s of Nursing Science Degree as an Educator.

She has traveled extensively, is a photographer, and writes on medical issues. Carol has three children RJ, Katherine, and Stephen – two daughters-in-law; Suzy and Katie – two granddaughters; Isabella Marianna and Zoe Olivia – and one grandson, Alexander Paul. She also shares her life with husband Gordon Duff, many cats, two rescue pups, and two guinea pigs.

Carol’s Archives 2009-2013

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  1. Gotta agree with you Carol being a confirmed smoker myself that vaping is definitely not the way to go if one wants to actually quit smoking. I have a friend who has more of jones for a vap than I ever had for cigarettes. He’s always puffing on that damn thing.

    Personally never been interested in quitting smoking myself but I heard you could get away with vaping in places that don’t allow smoking. Not true anymore but back when the trend first started I’d vap up in a Restaurant or Airport and nobody said a word because I wasn’t technically “smoking” but then I found that sucking in steam puts water in the lungs. Smoking does have some benefits since its a great source of Nicotinic Acid aka Niacin whereas vaping doesn’t oxidize the Nicotine so you end up putting straight nicotine into your lungs which is an insecticide. Nuff said.

    • Smoke, smoke, smoke that cigarette
      Puff,puff, puff
      and if you puff yourself to death
      Tell St.Peter at the Pearly Gates
      I’m sorry but you’re gonna have to wait
      while I have another cigarette.

    • Not really interested in quitting but thanks for the advice. You remind me of one of those ant-smoking ads which I thought was pretty funny about this guy being followed by some self righteous smoke-free Nazi hectoring and lecturing him after buying a pack of cigs that said one included with every pack.

      Seriously though.

      We’ve been using tobacco ceremonially, medicinally and for enjoyment in this country for millennia before that terrorist Columbus “discovered” it and will continue enjoying it since it’s part of our culture here.

    • Gall, i agree with you. I have no intension to quit smoking traditional cigarettes, so far. And i’m against vaping. Never tried it. Pals use IQUOS. A pack of average sigarettes costs now approx.$1.40 – 2.00 in my country. Maybe i quit if it will be $10.00 🙂

    • Andy. Here in America. I buy ’em on the Rez or make ’em myself with my Top-O-Matic which is the fun and easy way to roll cigs. By the way I’ve tried Russian Cigarettes and gotta say they ain’t bad. The worst have to be Malaysian cigarettes unless you like the taste of cloves or have a tooth ache 🙂

      My favorite all time smoke though are Cuban cigars. Montecristos which are hard to get in the “Land of the Free, Home of the Brave”.

    • @Gall: i roll the cigs myself, too. Sometimes. Actually, we have only a few tobacco companies left in Russia. Kaliningrad, St.Petersburg and Rostov. The rest are joint with foreign companies. Also i liked Balmoral cigars, which my friends brought me from Italy. Cuban cigars are expensive for us and hard to find good ones.

  2. FEH….a good cigar is better.
    But then it won’t be popular with the woke generation. Quite frankly, I believe vaping is no less dangerous than real cigarettes and it’s obvious now that it really is more dangerous as it leads people, especially the young and ignorant into believing it is safer.
    First they hooked them on snuff, now it’s vaping. what’s next?

  3. E-cigs are now dangerous?
    Oh well, better tax them to the hilt!
    ( How did I know this was going to happen? BORING! )

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