Blood Clots: A Major Negative Factor for COVID-19 Patients

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Health Editor’s Note: Should we be looking at COVID-19 as a vascular disease?  We focus on the lungs, because of difficulty in breathing, and then watch the patient’s body systems begin to shut down due to clotting of the blood which then starves the body tissues of oxygen and kills them.  I believe protocol at most healthcare facilities is to watch for increased clotting tendencies with lab work and then give anticoagulants.  COVID-19 is a many faceted, insidious virus that attacks all systems of the body……Carol 

Research Letter  JAMA Network

Critical Care Medicine

May 29, 2020

Venous Thrombosis Among Critically Ill Patients With Coronavirus Disease 2019 (COVID-19)

Julien Nahum, MD1Tristan Morichau-Beauchant, MD1Fabrice Daviaud, MD1et alPerrine Echegut, MD2Jérôme Fichet, MD1Jean-Michel Maillet, MD1Stéphane Thierry, MD1

Author Affiliations 

JAMA Netw Open. 2020;3(5):e2010478. doi:10.1001/jamanetworkopen.2020.10478

Introduction

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) was identified as a new coronavirus causing pneumonia and acute respiratory distress syndrome. It has become a pandemic, spreading particularly quickly across Europe and the US. Most deaths are related to severe acute respiratory distress syndrome, but other organ failures, such as acute kidney failure and acute cardiac injury, seem also related to the disease.1 Inflammatory response is highly increased in coronavirus disease 2019 (COVID-19) infection, and inflammation is known to favor thrombosis. High dimerized plasmin fragment D (D-dimer) levels and procoagulant changes in coagulation pathways were reported among patients with severe COVID-19.2,3 An elevated rate of venous and arterial thrombotic events associated with COVID-19 infection has also been reported.4,5 This case series reports a systematic assessment of deep vein thrombosis among patients in an intensive care unit (ICU) in France with severe COVID-19.

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