Mild Infections of COVID-19 May Not Offer Lasting Immunity

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Health Editor’s Note: Immunity against SARS-CoV-2 may not be long lasting in people who have a mild illness.   The majority of those who have coronavirus fall into that category. We can get the common cold, which is a coronavirus, over and over again, because we do not develop a lasting immunity. Generally, if we contract (or are vaccinated for) the viruses of measles, mumps, rubella, chicken pox, we will develop a life-long immunity to those viruses. 

What is revealed in this study is that the immunity levels, measured in the blood, decrease at a fairly rapid rate after the initial infection.  Since this study has only gone on for 90 days it is unsure if the decrease in antibodies will continue or if some antibodies will remain for long term and if they will be strong enough (longer lived) to fight further COVID-19 infections….Carol

Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

New England Journal of Medicine

July 21, 2020
DOI: 10.1056/NEJMc2025179
Metrics

A recent article suggested the rapid decay of anti–SARS-CoV-2 IgG in early infection,1 but the rate was not described in detail. We evaluated persons who had recovered from Covid-19 and referred themselves to our institution for observational research. Written informed consent was obtained from all the participants, with approval by the institutional review board. Blood samples were analyzed by enzyme-linked immunosorbent assay (ELISA) to detect anti–SARS-CoV-2 spike receptor-binding domain IgG.2 The ELISA was further modified to precisely quantify serum anti–receptor-binding domain activity in terms of equivalence to the concentration of a control anti–receptor-binding domain monoclonal IgG (CR3022, Creative Biolabs).

Infection had been confirmed by polymerase-chain-reaction assay in 30 of the 34 participants. The other 4 participants had had symptoms compatible with Covid-19 and had cohabitated with persons who were known to have Covid-19 but were not tested because of mild illness and the limited availability of testing. Most of the participants had mild illness; 2 received low-flow supplemental oxygen and leronlimab (a CCR5 antagonist), but they did not receive remdesivir. There were 20 women and 14 men. The mean age was 43 years (range, 21 to 68).

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Biography
Carol graduated from Riverside White Cross School of Nursing in Columbus, Ohio and received her diploma as a registered nurse. She attended Bowling Green State University where she received a Bachelor of Arts Degree in History and Literature. She attended the University of Toledo, College of Nursing, and received a Master’s of Nursing Science Degree as an Educator.

She has traveled extensively, is a photographer, and writes on medical issues. Carol has three children RJ, Katherine, and Stephen – one daughter-in-law; Katie – two granddaughters; Isabella Marianna and Zoe Olivia – and one grandson, Alexander Paul. She also shares her life with husband Gordon Duff, many cats, and two rescue pups.

Carol’s Archives 2009-2013
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3 COMMENTS

  1. By the source of the study alone is reason to suspect it’s veracity. The absence of meaningful, useful, and factual content and an almost definite maybe nuance is a very familiar presentation that’s pervasive among US Government, and NGO agencies, and organisations.
    Of these, all are in support of what US Government calls heathcare that goes against all known medical practices worldwide. The statistics shown by the above are manipulated, , with Government leaders ordering medical personnel to reflect a specific cause of death, regardless of the cause. Healthcare personnel are forced to comply with Government orders, and requirements, or face punishment. The loss of employment, in their chosen field, careers, and other reprisals. Falsifying Official Documents is a criminal act.
    Requiring Doctors to ask questions unrelated to healthcare report to Government, lie to, and misinformation, manipulate patients, in a deceptive manner to accecpt treatment known to to do harm, use “safety” practices known to be toxic, debilitating and can kill.
    Treatment of patients dictated by law enforcement, and spy agencies, with the support of health organisations. Overruling any treatment by doctors. Healthcare dispensed based on the individual’s social status, which is by undisclosed calculations, the patients are denied official access to. Government controlled mandated “healthcare” in US constitutes an act of treason, crime against humanity, supported by organisations committing criminal acts at all levels.
    The ultimate in surveillance and limited healthcare. Managed, and dispensed by spy, security, and law enforcement alphabet agencies. There are no health related agencies, or organisations involved in any of this. Intentionally exculded.
    Predictable, and mine is that this article will be shown to be
    deception.

    • But, Jim, what kind of a bioweapon would COVID-19 be if people developed immunity to it? It would be back to the drawing board in dozens of US bio-labs all around the world to find some horrible contagion that people had no immunity to and for which there would never be a vaccine developed.

      Don’t worry, the real “powers that be” will find something that culls the human herd of old people, the unemployable and especially people of color. Hell, the US did it back in the 19th Century giving small-pox infested blankets to the Indians, we can certainly do better than that.

    • Jim Allen, This is the beginning of study to see if there is lasting immunity when someone has a mild case of COVID-19. Obviously the data has only been collected for a few weeks, since that is how long we have been looking at COVID-19, a ‘novel’ coronavirus, not before seen or analyzed. Treatments were not established for this previously non-existent virus because, well, it is new. Going off on a tangent as to how it arrived is so unhelpful and at this point tiring. We are faced with an extremely contagious virus, that seeks out the old, the immuno-compromised, those with pre-existing health conditions and diseases, and often kills them. It did not come with a vaccine, a play book, and every treatment that is used has been used ‘for the first time’ for this virus. There are health agencies involved in finding the best practices of prevention and cure of COVID-19.

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