Health Editor’s Note: VT posted an earlier article informing about MIS-C and the NIH’s intent to find ways to predict which children will get MIS-C after contracting COVID-19. Some children become quite ill and die from MIS-C.
Trump downplays children getting COVID-19, saying they do not get as sick as adults. Not True! Trump thinks if the schools reopen, he will get gold star points that will be reflected at the voters’ polls in November. With the debate of opening schools during the continuing pandemic MIS-C should be a prime factor in decision making…Carol
COVID-19–Associated Multisystem Inflammatory Syndrome in Children — United States, March–July 2020
About 80% of reported flu deaths in children during the 2019-20 flu season occurred in kids who were not fully vaccinated against flu. Flu vaccination can be life-saving in children. Learn more about children & flu: https://t.co/0g2mvf5Cxi. https://t.co/nVH7xSMyt2— CDC (@CDCgov) August 10, 2020
In April 2020, during the peak of the coronavirus disease 2019 (COVID-19) pandemic in Europe, a cluster of children with hyperinflammatory shock with features similar to Kawasaki disease and toxic shock syndrome was reported in England* (1). The patients’ signs and symptoms were temporally associated with COVID-19 but presumed to have developed 2–4 weeks after acute COVID-19; all children had serologic evidence of infection with SARS-CoV-2, the virus that causes COVID-19 (1). The clinical signs and symptoms present in this first cluster included fever, rash, conjunctivitis, peripheral edema, gastrointestinal symptoms, shock, and elevated markers of inflammation and cardiac damage (1). On May 14, 2020, CDC published an online Health Advisory that summarized the manifestations of reported multisystem inflammatory syndrome in children (MIS-C), outlined a case definition,† and asked clinicians to report suspected U.S. cases to local and state health departments. As of July 29, a total of 570 U.S. MIS-C patients who met the case definition had been reported to CDC. A total of 203 (35.6%) of the patients had a clinical course consistent with previously published MIS-C reports, characterized predominantly by shock, cardiac dysfunction, abdominal pain, and markedly elevated inflammatory markers, and almost all had positive SARS-CoV-2 test results. The remaining 367 (64.4%) of MIS-C patients had manifestations that appeared to overlap with acute COVID-19 (2–4), had a less severe clinical course, or had features of Kawasaki disease.§ Median duration of hospitalization was 6 days; 364 patients (63.9%) required care in an intensive care unit (ICU), and 10 patients (1.8%) died. As the COVID-19 pandemic continues to expand in many jurisdictions, clinicians should be aware of the signs and symptoms of MIS-C and report suspected cases to their state or local health departments; analysis of reported cases can enhance understanding of MIS-C and improve characterization of the illness for early detection and treatment.