Timothy Brown Was a Champion for Keeping an HIV Cure on the Political and Scientific Agenda
Health Editor’s Note: Mr. Brown, also knows as the “Berlin Patient” was cured of HIV in 2008 after undergoing stem cell transplant for acute leukemia. Sadly, the recurrence of leukemia has taken his life.
The donor for his stem cell transplant (bone marrow) had a natural resistance to HIV infection because of a mutation in the CCR5 gene, which is a critical protein required by HIV to enter and infect cells. After Mr. Brown remained free of HIV virus, after stopping the antiretroviral therapy (ART) post stem cell transplant, his case opened the door to the possibility of a cure for HIV and this gave rise to HIV cure research….Carol