Raw Story: Could delivering Covid-19 immunity directly to the nose — the area of the body via which it is most likely to be transmitted — help conquer the pandemic?
The World Health Organization says clinical trials are underway to evaluate eight nasal spray vaccines that target Covid-19.
Could delivering Covid-19 immunity directly to the nose — the area of the body via which the virus is most likely to be transmitted — help conquer the pandemic?— AFP News Agency (@AFP) September 17, 2021
The WHO says clinical trials are underway to evaluate eight nasal spray vaccines https://t.co/ytStzWDoyQ pic.twitter.com/XSp3D7kufX
The most advanced effort so far by China’s Xiamen University, the University of Hong Kong and Beijing Wantai Biological Pharmacy has completed phase-2 trials.
“When the virus infects someone it usually gets in through the nose,” said researcher Nathalie Mielcarek who is working with the Lille Pasteur Institute to develop a nasal spray vaccine against whooping cough.
“The idea is to shut the door.”
An article published in Scientific American in March urged developing nasal spray vaccines because they have an immediate effect on the virus in an infected person’s mucus.
Possible nasal vax: A Covid nasal vaccine candidate is effective at preventing disease transmission, according the latest round of testing. The aim is to provide mucosal immunity in the nose, the 1st barrier against the virus before it reaches the lungs https://t.co/Hbrcvawojn— delthia ricks 🔬 (@DelthiaRicks) September 15, 2021
There they trigger production of an antibody known as immunoglobulin A, which can block infection.
“This overwhelming response, called sterilising immunity, reduces the chance that people will pass on the virus,” said the article.
The vaccines currently available offer strong protection against severe forms of Covid-19 but are less reliable at preventing the spread of the virus.
Stimulating immunity directly in the nose “lowers the risk of infecting other people”, said Mielcarek. Read more..